Product Description

PFKL (E724) Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS1943-50, BS1943-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: Phosphofructokinase (PFK) catalyzes the phosphorylation of fructose-6-phosphate in glycolysis. There are three isozymes: muscle-type, liver-type, and platelet-type. The liver-type PFK (PFKL) is the predominant subunit of PFK found in the liver. Research studies have shown that because of its location on chromosome 21, this enzyme is overexpressed in Down Syndrome/trisomy 21. PFKL also may have a role in the physiological response to a low fat diet.

Category: Primary Antibody

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: IHC

Alternate Names: 6-phosphofructokinase, liver type, Phosphofructokinase 1, Phosphohexokinase, Phosphofructo-1-kinase isozyme B, PFK-B,

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: Synthetic peptide, corresponding to amino acids 700-750 of Human PFKL.

Dilution: IHC: 1:50~1:200

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: PFKL (E724) polyclonal antibody detects endogenous levels of PFKL protein.

Molecular Weight: ~ 85 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: P17858

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Research Use Only