PGR Monoclonal Antibody - BT-MCA3630

PGR Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Number: BT-MCA3630-50, BT-MCA3630-100

Citations, Manuals and MSDS Available upon request.

Background: PGR: progesterone receptor. This gene encodes a member of the steroid receptor superfamily. The encoded protein mediates the physiological effects of progesterone, which plays a central role in reproductive events associated with the establishment and maintenance of pregnancy. This gene uses two distinct promotors and translation start sites in the first exon to produce two isoforms, A and B. The two isoforms are identical except for the additional 165 amino acids found in the N-terminus of isoform A only, and mediate their own response genes and physiologic effects with little overlap. The location of transcription initiation for isoform B has not been clearly determined.

Research Areas: Epigenetics and Nuclear Signaling

Target Protein: PGR

Reactivity: Human

Clonality: Monoclonal

Clone ID: 2C11F11

Host: Mouse

Isotype: Mouse IgG2b

Full Product Name: PGR

Immunogen: Purified recombinant fragment of PGR (aa731-909) expressed in E. Coli.

Storage: 4°C|-20°C for long term storage

Formulation: Ascitic fluid containing 0.03% sodium azide.

UniProt Accession: P06401

Synonyms: PR, NR3C3, PGR

GeneID: 5241

Research Use Only