Product Description

PHAPI2 Rabbit Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: ES4504-50, ES4504-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: function:Multifunctional protein working as a cell cycle progression factor as well as a cell survival factor. Required for the progression from the G1 to the S phase. Anti-apoptotic protein which functions as a caspase-3 inhibitor. Has no phosphatase 2A (PP2A) inhibitor activity.,similarity:Belongs to the ANP32 family.,similarity:Contains 4 LRR (leucine-rich) repeats.,subcellular location:Accumulates in the nuclei at the S phase.,tissue specificity:Expressed in heart, lung, pancreas, prostate and in spleen, thymus and placenta.,

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: WB, ELISA, IHC

Alternate Names: ANP32B, APRIL, PHAPI2, Acidic leucine-rich nuclear phosphoprotein 32 family member B, Acidic protein rich in leucines, Putative HLA-DR-associated protein I-2, PHAPI2, Silver-stainable protein SSP29

Clonality: Polyclonal

Immunogen: The antiserum was produced against synthesized peptide derived from human ANP32B. AA range:1-50

Isotype: IgG

Target: PHAPI2

Specificity: PHAPI2 Polyclonal Antibody detects endogenous levels of PHAPI2 protein.

Dilution: WB 1:500-2000, IHC-p 1:50-300, ELISA 2000-20000

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration: 1 mg/ml,

Formlation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Expression: Expressed in heart, lung, pancreas, prostate and in spleen, thymus and placenta,

Observed Band (KD): 29kD

Function: Function: Multifunctional protein working as a cell cycle progression factor as well as a cell survival factor. Required for the progression from the G1 to the S phase. Anti-apoptotic protein which functions as a caspase-3 inhibitor. Has no phosphatase 2A (PP2A) inhibitor activity
Similarity: Belongs to the ANP32 family
Similarity: Contains 4 LRR (leucine-rich) repeats
Subcellular Location: Accumulates in the nuclei at the S phase
Tissue Specificity: Expressed in heart, lung, pancreas, prostate and in spleen, thymus and placenta

Subcellular Location: [Isoform 1]: Nucleus Cytoplasm Accumulates in the nuclei at the S phase, [Isoform 2]: Cytoplasm Lacks a nuclear localization signal

Storage and Stability: -20°C/1 year

Gene Name: ANP32B

Protein Name: Acidic leucine-rich nuclear phosphoprotein 32 family member B

Mouse Gene ID: 67628

Mouse SwissProt Number: Q9EST5

Rat Gene ID: 170724

Rat SwissProt Number: Q9EST6

Research Use Only