Phospho-Artemis (S516) Polyclonal Antibody - BT-PHS00643

Phospho-Artemis (S516) Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-PHS00643-20, BT-PHS00643-50, BT-PHS00643-100

Citations, Manuals and MSDS Available upon request.

Background: DCLRE1C encodes a nuclear protein that is involved in V(D)J recombination and DNA repair. The encoded protein has single-strand-specific 5'-3' exonuclease activity; it also exhibits endonuclease activity on 5' and 3' overhangs and hairpins. The protein also functions in the regulation of the cell cycle in response to DNA damage. Mutations in DCLRE1C can cause Athabascan-type severe combined immunodeficiency (SCIDA) and Omenn syndrome. Alternative splicing results in multiple transcript variants.

Research Areas: Epigenetics and Nuclear Signaling

Target Protein: DCLRE1C

Applications: WB, IHC-p, ELISA

Reactivity: Human, mouse

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: Phospho-Artemis (S516) Antibody

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

Molecular Weight (Da): 78436

UniProt Accession: Human: Q96SD1; Mouse: Q8K4J0

Synonyms: DCLRE1C; ARTEMIS; ASCID; SCIDA; SNM1C; Protein artemis; DNA cross-link repair 1C protein; Protein A-SCID; SNM1 homolog C; hSNM1C; SNM1-like protein

GeneID: Human: 64421; Mouse: 227525

Research Use Only