Phospho-Axl (Y691) Polyclonal Antibody - BT-PHS00779

Phospho-Axl (Y691) Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-PHS00779-20, BT-PHS00779-50, BT-PHS00779-100

Citations, Manuals and MSDS Available upon request.

Background: The protein encoded by AXL (AXL receptor tyrosine kinase) is a member of the Tyro3-Axl-Mer (TAM) receptor tyrosine kinase subfamily. The encoded protein possesses an extracellular domain which is composed of two immunoglobulin-like motifs at the N-terminal, followed by two fibronectin type-III motifs. It transduces signals from the extracellular matrix into the cytoplasm by binding to the vitamin K-dependent protein growth arrest-specific 6 (Gas6). AXL may be involved in several cellular functions including growth, migration, aggregation and anti-inflammation in multiple cell types. Alternative splicing results in multiple transcript variants of AXL.

Research Areas: Cell Biology; Signal Transduction

Target Protein: AXL

Applications: WB, IHC-p, ELISA

Reactivity: Human, mouse, rat

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: Phospho-Axl (Y691) Antibody

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

Molecular Weight (Da): 97437

UniProt Accession: Human: P30530; Mouse: Q00993

Synonyms: AXL; UFO; Tyrosine-protein kinase receptor UFO; AXL oncogene

GeneID: Human: 558; Mouse: 26362

Research Use Only