Phospho-B-Myb (S577) Polyclonal Antibody - BT-PHS00540

Phospho-B-Myb (S577) Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-PHS00540-20, BT-PHS00540-50, BT-PHS00540-100

Citations, Manuals and MSDS Available upon request.

Background: The protein encoded by MYBL2, a member of the MYB family of transcription factor genes, is a nuclear protein involved in cell cycle progression. The encoded protein is phosphorylated by cyclin A/cyclin-dependent kinase 2 during the S-phase of the cell cycle and possesses both activator and repressor activities. It has been shown to activate the cell division cycle 2, cyclin D1, and insulin-like growth factor-binding protein 5 genes. Two transcript variants encoding different isoforms have been found for this gene.

Research Areas: Cell Biology; Cancer

Target Protein: MYBL2

Applications: WB, IF, ELISA

Reactivity: Human, mouse, rat

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: Phospho-B-Myb (S577) Antibody

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

Molecular Weight (Da): 78764

UniProt Accession: Human: P10244; Mouse: P48972

Synonyms: MYBL2; BMYB; Myb-related protein B; B-Myb; Myb-like protein 2

GeneID: Human: 4605; Mouse: 17865

Research Use Only