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Phospho-Bmx (Y566) Polyclonal Antibody - BT-PHS00717
Phospho-Bmx (Y566) Polyclonal Antibody - BT-PHS00717
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Phospho-Bmx (Y566) Polyclonal Antibody
Sizes: 20μL, 50μL, 100μL
Catalogue Numbers: BT-PHS00717-20, BT-PHS00717-50, BT-PHS00717-100
Citations, Manuals and MSDS Available upon request.
Background: BMX (BMX non-receptor tyrosine kinase) encodes a non-receptor tyrosine kinase belonging to the Tec kinase family. The protein contains a PH-like domain, which mediates membrane targeting by binding to phosphatidylinositol 3,4,5-triphosphate (PIP3), and a SH2 domain that binds to tyrosine-phosphorylated proteins and functions in signal transduction. The protein is implicated in several signal transduction pathways including the Stat pathway, and regulates differentiation and tumorigenicity of several types of cancer cells. Alternatively spliced transcript variants have been found for BMX.
Research Areas: Signal Transduction
Target Protein: BMX
Applications: WB, IHC-p, ELISA
Reactivity: Human, mouse
Clonality: Polyclonal
Host: Rabbit
Isotype: IgG
Full Product Name: Phospho-Bmx (Y566) Antibody
Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189
Storage: -20°C for 1 year
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration: 1 mg/ml
Molecular Weight (Da): 78011
UniProt Accession: Human: P51813; Mouse: P97504
Synonyms: BMX; Cytoplasmic tyrosine-protein kinase BMX; Bone marrow tyrosine kinase gene in chromosome X protein; Epithelial and endothelial tyrosine kinase; ETK; NTK38
GeneID: Human: 660; Mouse: 12169
Research Use Only
