Product Description

Phospho-Caldesmon (Thr753) Recombinant Rabbit mAb

Sizes: 50μl, 100μl

Catalogue Numbers: BS43230-50, BS43230-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: This gene encodes a calmodμlin- and actin-binding protein that plays an essential role in the regμlation of smooth muscle and nonmuscle contraction. The conserved domain of this protein possesses the binding activities to Ca(2+)-calmodμlin, actin, tropomyosin, myosin, and phospholipids. This protein is a potent inhibitor of the actin-tropomyosin activated myosin MgATPase, and serves as a mediating factor for Ca(2+)-dependent inhibition of smooth muscle contraction. Alternative splicing of this gene resμlts in mμltiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jμl 2008]

Category: Primary Antibody

Reactivity: Human

Host: Rabbit

Applications: WB, ICC/IF

Alternate Names: CDM, HCAD, LCAD, H-CAD, L-CAD, NAG22

Clonality: Monoclonal

Conjugate: Unconjugated

Modification: Phosphorylated

Immunogen: A synthetic phosphopeptide corresponding to residues surrounding
Thr753 of human Caldesmon

Dilution: WB: 1:1000 ICC/IF: 1:20-1:100

Purification: Affinity Purification

Specificity: IgG

Molecular Weight: 80 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: Q05682

Product: Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Research Use Only