Phospho-CaMKIIAlpha/Delta (T286) Polyclonal Antibody - BT-PHS00042

Phospho-CaMKIIAlpha/Delta (T286) Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-PHS00042-20, BT-PHS00042-50, BT-PHS00042-100

Citations, Manuals and MSDS Available upon request.

Background: The product of CAMK2A (calcium/calmodulin dependent protein kinase II alpha) belongs to the serine/threonine protein kinases family, and to the Ca(2+)/calmodulin-dependent protein kinases subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. This calcium calmodulin-dependent protein kinase is composed of four different chains: alpha, beta, gamma, and delta. The alpha chain encoded by this gene is required for hippocampal long-term potentiation (LTP) and spatial learning. In addition to its calcium-calmodulin (CaM)-dependent activity, this protein can undergo autophosphorylation, resulting in CaM-independent activity. Two transcript variants encoding distinct isoforms have been identified for CAMK2A.

Research Areas: Others

Target Protein: CAMK2A

Applications: WB, IHC-p, IF, ELISA

Reactivity: Human, mouse, rat

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: Phospho-CaMKIIalpha/delta (T286) Antibody

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

Molecular Weight (Da): 54030

UniProt Accession: Human: Q9UQM7/Q13557; Rat: P11275/P15791

Synonyms: CAMK2A; CAMKA; KIAA0968; Calcium/calmodulin-dependent protein kinase type II subunit alpha; CaM kinase II subunit alpha; CaMK-II subunit alpha; CAMK2D; CAMKD; Calcium/calmodulin-dependent protein kina

GeneID: Human: 815/817; Mouse: 12322/108058; Rat: 25400/24246

Research Use Only