Phospho-Caveolin-2 (Y27) Polyclonal Antibody - BT-PHS00454

Phospho-Caveolin-2 (Y27) Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-PHS00454-20, BT-PHS00454-50, BT-PHS00454-100

Citations, Manuals and MSDS Available upon request.

Background: The protein encoded by CAV2 (caveolin 2) is a major component of the inner surface of caveolae, small invaginations of the plasma membrane, and is involved in essential cellular functions, including signal transduction, lipid metabolism, cellular growth control and apoptosis. This protein may function as a tumor suppressor. CAV2 and related family member (CAV1) are located next to each other on chromosome 7, and express colocalizing proteins that form a stable hetero-oligomeric complex. Alternatively spliced transcript variants encoding different isoforms have been identified for CAV2. Additional isoforms resulting from the use of alternate in-frame translation initiation codons have also been described, and shown to have preferential localization in the cell (PMID: 11238462).

Research Areas: Tags and Cell Markers; Cardiovascular

Target Protein: CAV2

Applications: WB, ELISA

Reactivity: Human

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: Phospho-Caveolin-2 (Y27) Antibody

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

Molecular Weight (Da): 18291

UniProt Accession: Human: P51636; Mouse: Q9WVC3

Synonyms: CAV2; Caveolin-2

GeneID: Human: 858

Research Use Only