Phospho-CD3 Zeta (Y142) Polyclonal Antibody - BT-PHS00051

Phospho-CD3 Zeta (Y142) Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-PHS00051-20, BT-PHS00051-50, BT-PHS00051-100

Citations, Manuals and MSDS Available upon request.

Background: The protein encoded by CD247 (CD247 molecule) is T-cell receptor zeta, which together with T-cell receptor alpha/beta and gamma/delta heterodimers, and with CD3-gamma, -delta and -epsilon, forms the T-cell receptor-CD3 complex. The zeta chain plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. Low expression of the antigen results in impaired immune response. Two alternatively spliced transcript variants encoding distinct isoforms have been found for CD247.

Research Areas: Immunology

Target Protein: CD247

Applications: WB, IHC-p, ELISA

Reactivity: Human, mouse, rat, monkey

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: Phospho-CD3 zeta (Y142) Antibody

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

Molecular Weight (Da): 18696

UniProt Accession: Human: P20963; Mouse: P24161

Synonyms: CD247; CD3Z; T3Z; TCRZ; T-cell surface glycoprotein CD3 zeta chain; T-cell receptor T3 zeta chain; CD antigen CD247

GeneID: Human: 919; Mouse: 12503

Research Use Only