Phospho-CD44 (S706) Polyclonal Antibody - BT-PHS00349

Phospho-CD44 (S706) Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-PHS00349-20, BT-PHS00349-50, BT-PHS00349-100

Citations, Manuals and MSDS Available upon request.

Background: The protein encoded by CD44 (CD44 molecule (Indian blood group)) is a cell-surface glycoprotein involved in cell-cell interactions, cell adhesion and migration. It is a receptor for hyaluronic acid andnbsp;(HA) and can also interact with other ligands, such as osteopontin, collagens, and matrix metalloproteinases andnbsp;(MMPs). This protein participates in a wide variety of cellular functions including lymphocyte activation, recirculation and homing, hematopoiesis, and tumor metastasis. Transcripts for CD44 undergo complex alternative splicing that results in many functionally distinct isoforms, however, the full length nature of some of these variants has not been determined. Alternative splicing is the basis for the structural and functional diversity of this protein, and may be related to tumor metastasis.

Research Areas: Immunology

Target Protein: CD44

Applications: WB, ELISA

Reactivity: Human, mouse, rat

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: Phospho-CD44 (S706) Antibody

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

Molecular Weight (Da): 81554

UniProt Accession: Human: P16070; Mouse: P15379; Rat: P26051

Synonyms: CD44; LHR; MDU2; MDU3; MIC4; CD44 antigen; CDw44; Epican; Extracellular matrix receptor III; ECMR-III; GP90 lymphocyte homing/adhesion receptor; HUTCH-I; Heparan sulfate proteoglycan; Hermes antigen;

GeneID: Human: 960; Mouse: 12505

Research Use Only