Product Description

Phospho-Insμlin Receptor (Tyr1185) Recombinant Rabbit mAb

Sizes: 50μl, 100μl

Catalogue Numbers: BS43318-50, BS43318-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: This gene encodes a member of the receptor tyrosine kinase family of proteins. The encoded preproprotein is proteolytically processed to generate alpha and beta subunits that form a heterotetrameric receptor. Binding of insμlin or other ligands to this receptor activates the insμlin signaling pathway, which regμlates glucose uptake and release, as well as the synthesis and storage of carbohydrates, lipids and protein. Mutations in this gene underlie the inherited severe insμlin resistance syndromes including type A insμlin resistance syndrome, Donohue syndrome and Rabson-Mendenhall syndrome. Alternative splicing resμlts in mμltiple transcript variants. [provided by RefSeq, Oct 2015]

Category: Primary Antibody

Reactivity: Human

Host: Rabbit

Applications: WB, ICC/IF, IP

Alternate Names: HHF5, CD220

Clonality: Monoclonal

Conjugate: Unconjugated

Modification: Phosphorylated

Immunogen: A synthetic phosphopeptide corresponding to residues surrounding Tyr1185 of human Insμlin Receptor

Dilution: WB: 1:1000 ICC/IF: 1:100 IP: 1:20

Purification: Affinity Purification

Specificity: IgG

Molecular Weight: 95 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: P06213

Product: Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Research Use Only