Product Description

Phospho-Integrin alpha 4 (Ser1027) Recombinant Rabbit mAb

Sizes: 50μl, 100μl

Catalogue Numbers: BS43228-50, BS43228-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: The gene encodes a member of the integrin alpha chain family of proteins. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 4 subunit. This subunit associates with a beta 1 or beta 7 subunit to form an integrin that may play a role in cell motility and migration. This integrin is a therapeutic target for the treatment of mμltiple sclerosis, Crohn's disease and inflammatory bowel disease. Alternative splicing resμlts in mμltiple transcript variants. [provided by RefSeq, Oct 2015]

Category: Primary Antibody

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: WB

Alternate Names: IA4, CD49D

Clonality: Monoclonal

Conjugate: Unconjugated

Modification: Phosphorylated

Immunogen: A synthetic phosphopeptide corresponding to residues surrounding
Ser1027 of human Integrin alpha 4

Dilution: WB: 1:1000

Purification: Affinity Purification

Specificity: IgG

Molecular Weight: 150, 70 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: P13612

Product: Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Research Use Only