Product Description

Phospho-LAT (Tyr200) Recombinant Rabbit mAb

Sizes: 50μl, 100μl

Catalogue Numbers: BS43133-50, BS43133-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: The protein encoded by this gene is phosphorylated by ZAP-70/Syk protein tyrosine kinases following activation of the T-cell antigen receptor (TCR) signal transduction pathway. This transmembrane protein localizes to lipid rafts and acts as a docking site for SH2 domain-containing proteins. Upon phosphorylation, this protein recruits mμltiple adaptor proteins and downstream signaling molecμles into mμltimolecμlar signaling complexes located near the site of TCR engagement. Alternative splicing resμlts in mμltiple transcript variants encoding different isoforms. [provided by RefSeq, Jμl 2008]

Category: Primary Antibody

Reactivity: Human

Host: Rabbit

Applications: WB, ICC/IF

Alternate Names: LAT1, pp36, IMD52

Clonality: Monoclonal

Conjugate: Unconjugated

Modification: Phosphorylated

Immunogen: A synthetic phosphopeptide corresponding to residues surrounding
Tyr200 of human LAT

Dilution: WB: 1:2000 ICC/IF: 1:50

Purification: Affinity Purification

Specificity: IgG

Molecular Weight: 36-38 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: O43561

Product: Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Research Use Only