Product Description

phospho-MAK (Tyr159) Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS65822-50, BS65822-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: The product of this gene is a serine/threonine protein kinase related to kinases involved in cell cycle regμlation. It is expressed almost exclusively in the testis, primarily in germ cells. Studies of the mouse and rat homologs have localized the kinase to the chromosomes during meiosis in spermatogenesis, specifically to the synaptonemal complex that exists while homologous chromosomes are paired. There is, however, a study of the mouse homolog that has identified high levels of expression in developing sensory epithelia so its function may be more generalized. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jμl 2011]

Category: Primary Antibody

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: WB

Alternate Names: MAK (phospho Tyr159), MAK (phospho Y159), dJ417M14.2, Mak, MAK_HUMAN, Male germ cell associated kinase, Male germ cell-associated kinase, OTTHUMP00000016025, Rck, Serine/threonine protein kinase MAK, Serine/threonine-protein kinase MAK.

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Phosphorylation

Immunogen: KLH conjugated synthesised phosphopeptide derived from human MAK around the phosphorylation site of Tyr159:TD(p-Y)VS

Dilution: WB=1:500-2000

Purification: affinity purified by Protein A

Specificity: phospho-MAK (Tyr159) Polyclonal Antibody detects endogenous levels of MAK protein only when phosphorylated at Y159.

Molecular Weight: ~73 kDa

Pathway: Regμlation of Microtubμle Dynamics, Signaling Pathways Activating p38 MAP Kinase

Storage and Stability: Store at 4°C short term. Aliquot and store at -5°C long term. Avoid freeze-thaw cycles.

SwissProt: P20794

Product: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Research Use Only