Product Description

Phospho-MCM2 (Ser108) Recombinant Rabbit mAb

Sizes: 50μl, 100μl

Catalogue Numbers: BS43174-50, BS43174-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein forms a complex with MCM4, 6, and 7, and has been shown to regμlate the helicase activity of the complex. This protein is phosphorylated, and thus regμlated by, protein kinases CDC2 and CDC7. Mμltiple alternatively spliced transcript variants have been found, but the fμll-length nature of some variants has not been defined. [provided by RefSeq, Oct 2012]

Category: Primary Antibody

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: WB, ICC/IF, IP

Alternate Names: BM28, CCNL1, CDCL1, cdc19, DFNA70, D3S3194, MITOTIN

Clonality: Monoclonal

Conjugate: Unconjugated

Modification: Phosphorylated

Immunogen: A synthetic phosphopeptide corresponding to residues surrounding
Ser108 of human MCM2

Dilution: WB: 1:1000 ICC/IF: 1:50 IP: 1:20

Purification: Affinity Purification

Specificity: IgG

Molecular Weight: 125 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: P49736

Product: Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Research Use Only