Product Description

phospho-Nrf2 (Ser40) Monoclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS65507-50, BS65507-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: Nuclear factor erythroid 2-related factor 2 (Nrf2) is a transcription factor which regμlates the expression of many detoxification and antioxidant enzymes. Nrf2 can potentially play a significant role in adaptive responses to oxidative stress. Nrf2 belongs to the Cap N Collar (CNC-bZIP) subfamily of basic /leucine zipper (bZIP) transcription factors.

Category: Primary Antibody

Reactivity: Human

Host: Rabbit

Applications: IHC-P

Alternate Names: Nrf2 (phospho S40), p-Nrf2 (phospho S40), Nuclear factor-E2 related factor2, HEBP1, NF E2 related factor 2, NFE2 related factor 2, NFE2L2, Nrf 2, Nuclear factor erythroid 2 related factor 2, Nuclear factor erythroid derived 2 like 2, NF2L2_HUMAN.

Clonality: Monoclonal

Conjugate: Unconjugated

Modification: Phosphorylation

Immunogen: KLH conjugated Synthesised phosphopeptide derived from human Nrf2 around the phosphorylation site of Ser40:DF(p-S)QR

Dilution: IHC-P=1:100-500
not yet tested in other applications.
optimal dilutions/concentrations shoμld be determined by the end user.

Purification: affinity purified by Protein A

Specificity: Phospho-Nrf2 (Ser40) monoclonal antibody detects endogenous levels of Nrf2 protein only when phosphorylated at Ser40.

Molecular Weight: ~100 kDa

Pathway: AMPK Signaling Pathway,

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: Q16236

Product: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Research Use Only