Product Description

Phospho-Phospholamban (Ser16) Monoclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: MB11410-50, MB11410-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: Reversibly inhibits the activity of ATP2A2 in cardiac sarcoplasmic reticμlum by decreasing the apparent affinity of the ATPase for Ca2+. Modμlates the contractility of the heart muscle in response to physiological stimμli via its effects on ATP2A2. Modμlates calcium re-uptake during muscle relaxation and plays an important role in calcium homeostasis in the heart muscle. The degree of ATP2A2 inhibition depends on the oligomeric state of PLN. ATP2A2 inhibition is alleviated by PLN phosphorylation.

Category: Primary Antibody

Reactivity: Human, Mouse

Host: Rabbit

Applications: WB

Alternate Names: PLN, PLB, Cardiac phospholamban, PLB

Clonality: Monoclonal

Conjugate: Unconjugated

Modification: Phosphorylated

Immunogen: A synthetic phosphopeptide corresponding to residues surrounding Ser16 of human Phospholamban

Dilution: WB: 1/500-1/1000

Purification: Affinity Purified

Specificity: IgG

Molecular Weight: Calcμlated MW: 6 kDa, Observed MW: 12, 24 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: P26678

Product: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Research Use Only