Product Description

Phospho-PIM1 (Tyr309) Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS65627-50, BS65627-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: The protein encoded by this gene belongs to the Ser/Thr protein kinase family, and PIM subfamily. This gene is expressed primarily in B-lymphoid and myeloid cell lines, and is overexpressed in hematopoietic malignancies and in prostate cancer. It plays a role in signal transduction in blood cells, contributing to both cell proliferation and survival, and thus provides a selective advantage in tumorigenesis. Both the human and orthologous mouse genes have been reported to encode two isoforms (with preferential cellμlar localization) resμlting from the use of alternative in-frame translation initiation codons, the upstream non-AUG (CUG) and downstream AUG codons (PMIDs:16186805, 1825810).[provided by RefSeq, Aug 2011].

Category: Primary Antibody

Reactivity: Human, Mouse, Rat, Dog, Pig, Cow, Rabbit, Sheep

Host: Rabbit

Applications: FCM

Alternate Names: PIM1 (phospho Y309), PIM1 (phospho Tyr309), Oncogene PIM 1, Oncogene PIM1, PIM 1, Pim 1 kinase, Pim 1 oncogene, PIM, Pim2, PIM3, Proto oncogene serine/threonine protein kinase Pim 1, Proviral integration site 1, Proviral integration site 2

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Phosphorylation

Immunogen: KLH conjugated Synthesised phosphopeptide derived from human PIM1 around the phosphorylation site of Tyr309

Dilution: Flow-Cyt=1ug/Test

Purification: affinity purified by Protein A

Specificity: Phospho-PIM1 (Tyr309) Polyclonal Antibody detects endogenous levels of Phospho-PIM1 protein only when phosphorylated at Tyr309

Molecular Weight: 45kD

Pathway: Examples of Crosstalk Between Post-translational Modifications,

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: P11309

Product: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Research Use Only