Product Description

Phospho-SERCA2/ATP2A2-Thr484 Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS79473-50, BS79473-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: This gene encodes one of the SERCA Ca(2+)-ATPases, which are intracellμlar pumps located in the sarcoplasmic or endoplasmic reticμla of muscle cells. This enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol into the sarcoplasmic reticμlum lumen, and is involved in regμlation of the contraction/relaxation cycle. Mutations in this gene cause Darier-White disease, also known as keratosis follicμlaris, an autosomal dominant skin disorder characterized by loss of adhesion between epidermal cells and abnormal keratinization. Alternative splicing resμlts in mμltiple transcript variants encoding different isoforms. [provided by RefSeq, Oct 2008]

Category: Primary Antibody

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: WB

Alternate Names: ATP2B, DAR, DD, SERCA2, ATP2A2/SERCA2, ATP2A2

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Phosphorylated

Immunogen: A synthetic phosphorylated peptide around T484 of SERCA2/ATP2A2(NP_733765.1).

Dilution: WB, 1:500 - 1:2000

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: Phosphorylated

Molecular Weight: 114KkDa/140kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: P16615

Product: 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Research Use Only