Phospho-Smad1 (Ser463/Ser465) Monoclonal Antibody-MB11894

Phospho-Smad1 (Ser463/Ser465) Monoclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: MB11894-50, MB11894-100

Product: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Swiss-Prot: Q15797

Host: Rabbit

Reactivity: Human, Rat

Applications: WB,IP

All Applications: WB: 1/500-1/1000 IP: 1/20

Background: Transcriptional modulator activated by BMP (bone morphogenetic proteins) type 1 receptor kinase. SMAD1 is a receptor-regulated SMAD (R-SMAD). SMAD1/OAZ1/PSMB4 complex mediates the degradation of the CREBBP/EP300 repressor SNIP1. May act synergistically with SMAD4 and YY1 in bone morphogenetic protein (BMP)-mediated cardiac-specific gene expression.

Purification and Purity: Affinity Purified

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of Phospho-Smad1 in A549, U2OS, C6Lysates using Phospho-Smad1 antibody.

Bioworld Molecular Weight: Calculated MW: 52 kDa; Observed MW: 52 kDa

Specificity: IgG

Alternative Name: SMAD1; BSP1; MADH1; MADR1; Mothers against decapentaplegic homolog 1; MAD homolog 1; Mothers against DPP homolog 1; JV4-1; Mad-related protein 1; SMAD family member 1; SMAD 1; Smad1; hSMAD1; Transforming growth factor-beta-signaling protein

Immunogen: A synthetic phosphopeptide corresponding to residues surrounding Ser463/Ser465 of human Smad1

Conjugate: Unconjugated

Modification: Phosphorylated