Product Description

Phospho-STING/TMEM173-S366 Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS79500-50, BS79500-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: This gene encodes a five transmembrane protein that functions as a major regμlator of the innate immune response to viral and bacterial infections. The encoded protein is a pattern recognition receptor that detects cytosolic nucleic acids and transmits signals that activate type I interferon responses. The encoded protein has also been shown to play a role in apoptotic signaling by associating with type II major histocompatibility complex. Mutations in this gene are the cause of infantile-onset STING-associated vascμlopathy. Alternate splicing resμlts in mμltiple transcript variants.

Category: Primary Antibody

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: WB

Alternate Names: TMEM173, ERIS, MITA, MPYS, NET23, SAVI, STING, hMITA, hSTING

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Phosphorylated

Immunogen: A synthetic phosphorylated peptide around S366 of human STING/TMEM173(NP_938023.1).

Dilution: WB, 1:500 - 1:1000

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: Phospho-STING/TMEM173-S366 polyclonal antibody detects endogenous levels of STING/TMEM173 protein only when phosphorylated at S366.

Molecular Weight: 33KDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: Q86WV6

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Research Use Only