Product Description

Phospho-TAK1 (Ser439) Monoclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: MB11666-50, MB11666-100

Product: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Swiss-Prot: O43318

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB,ICC/IF,IP

All Applications: WB: 1/500-1/1000 IF: 1/50-1/200 IP: 1/20

Background: Component of a protein kinase signal transduction cascade. Mediator of TRAF6 and TGF-beta signal transduction. Activates IKBKB and MAPK8 in response to TRAF6 signaling. Stimulates NF-kappa-B activation and the p38 MAPK pathway. In osmotic stress signaling, plays a major role in the activation of MAPK8/JNK, but not that of NF-kappa-B.

Purification and Purity: Affinity Purified

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of TAK1 in 3T3, C6, MCF-7Lysates using Phospho-TAK1 antibody.

Bioworld Molecular Weight: Calculated MW: 67 kDa; Observed MW: 78 kDa

Specificity: IgG

Alternative Name: MAP3K7; TAK1; Mitogen-activated protein kinase kinase kinase 7; Transforming growth factor-beta-activated kinase 1; TGF-beta-activated kinase 1

Immunogen: A synthetic phosphopeptide corresponding to residues surrounding Ser439 of human TAK1

Conjugate: Unconjugated

Modification: Phosphorylated