Phospho-Tau-T231 Polyclonal Antibody Sizes: 50µl, 100µl Catalogue Numbers: BS79458-50, BS79458-100 Product: 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2 Swiss-Prot: P10636 Host: Rabbit Reactivity: Mouse Applications: WB All Applications: WB,1:500 - 1:2000 Background: This gene encodes the microtubule-associated protein tau (MAPT) whose transcript undergoes complex, regulated alternative splicing, giving rise to several mRNA species. MAPT transcripts are differentially expressed in the nervous system, depending on stage of neuronal maturation and neuron type. MAPT gene mutations have been associated with several neurodegenerative disorders such as Alzheimer's disease, Pick's disease, frontotemporal dementia, cortico-basal degeneration and progressive supranuclear palsy. [provided by RefSeq, Jul 2008] Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE). Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Note: For research use only, not for use in diagnostic procedure. Extra Notes: Western blot analysis of extracts of Mouse brain, using Phospho-Tau-Thr231 antibody at 1:1000 dilution. Mouse brain were treated by CIP at 37℃ for 1 hour. Secondary antibody: HRP Goat Anti-Rabbit IgG at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% BSA. Detection: ECL Basic Kit. Exposure time: 1s. Bioworld Molecular Weight: 60kDa Specificity: Phosphorylated Alternative Name: DDPAC; FTDP-17; MAPTL; MSTD; MTBT1; MTBT2; PPND; PPP1R103; TAU; MAPT; Tau Immunogen: A synthetic phosphorylated peptide around T548 of human Tau(NP_058519.3?). Conjugate: Unconjugated Modification: Phosphorylated