Product Description

Phospho-Tyk2-Y1054/1055 Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS79399-50, BS79399-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: This gene encodes a member of the tyrosine kinase and, more specifically, the Janus kinases (JAKs) protein families. This protein associates with the cytoplasmic domain of type I and type II cytokine receptors and promμlgate cytokine signals by phosphorylating receptor subunits. It is also component of both the type I and type III interferon signaling pathways. As such, it may play a role in anti-viral immunity. A mutation in this gene has been associated with hyperimmunoglobμlin E syndrome (HIES) - a primary immunodeficiency characterized by elevated serum immunoglobμlin E.

Category: Primary Antibody

Reactivity: Mouse

Host: Rabbit

Applications: WB

Alternate Names: TYK2, IMD35, JTK1

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Phosphorylated

Immunogen: A synthetic phosphorylated peptide around Y1054 & Y1055 of human Tyk2(NP_003322.3).

Dilution: WB, 1:500 - 1:1000

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: Phosphorylated

Molecular Weight: 134KDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: P29597

Product: 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Research Use Only