Phospho-VEGF Receptor 2-Y996 Polyclonal Antibody-BS79413

Phospho-VEGF Receptor 2-Y996 Polyclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: BS79413-50, BS79413-100

Product: 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: P35968

Host: Rabbit

Reactivity: Human

Applications: WB

All Applications: WB,1:500 - 1:2000

Background: Vascular endothelial growth factor (VEGF) is a major growth factor for endothelial cells. This gene encodes one of the two receptors of the VEGF. This receptor, known as kinase insert domain receptor, is a type III receptor tyrosine kinase. It functions as the main mediator of VEGF-induced endothelial proliferation, survival, migration, tubular morphogenesis and sprouting. The signalling and trafficking of this receptor are regulated by multiple factors, including Rab GTPase, P2Y purine nucleotide receptor, integrin alphaVbeta3, T-cell protein tyrosine phosphatase, etc.. Mutations of this gene are implicated in infantile capillary hemangiomas.

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of extracts of HUVEC cell line, using Phospho-VEGF Receptor 2-Y996 antibody.
Secondary antibody: HRP Goat Anti-Rabbit IgG at 1:10000 dilution.
Lysates/proteins: 25ug per lane.
Blocking buffer: 3% BSA.

Bioworld Molecular Weight: 200kDa

Specificity: Phosphorylated

Alternative Name: CD309; FLK1; VEGFR; VEGFR2; VEGF Receptor 2; KDR

Immunogen: A synthetic phosphorylated peptide around Y996 of human VEGF Receptor 2(NP_002244.1).

Conjugate: Unconjugated

Modification: Phosphorylated