Product Description

Phospho-YAP1 (Ser127) Monoclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: MB11789-50, MB11789-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: YAP (Yes-associated protein, YAP65) was identified based on its ability to associate with the SH3 domain of Yes. Transcriptional regμlator which can act both as a coactivator and a corepressor and is the critical downstream regμlatory target in the Hippo signaling pathway that plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis.

Category: Primary Antibody

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: WB, IHC-P

Alternate Names: YAP1, YAP65, Yorkie homolog, 65 kDa Yes-associated protein, YAP65

Clonality: Monoclonal

Conjugate: Unconjugated

Modification: Phosphorylated

Immunogen: A synthetic phosphopeptide corresponding to residues surrounding Ser127 of human YAP1

Dilution: WB: 1/500-1/1000 IHC: 1/50-1/100

Purification: Affinity Purified

Specificity: IgG

Molecular Weight: Calcμlated MW: 54 kDa, Observed MW: 70-75 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: P46937

Product: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Research Use Only