PHX2A Polyclonal Antibody - BT-AP13003

PHX2A Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP13003-20, BT-AP13003-50, BT-AP13003-100

Citations, Manuals and MSDS Available upon request.

Background: The protein encoded by this gene contains a paired-like homeodomain most similar to that of the Drosophila aristaless gene product. The encoded protein plays a central role in development of the autonomic nervous system. It regulates the expression of tyrosine hydroxylase and dopamine beta-hydroxylase, two catecholaminergic biosynthetic enzymes essential for the differentiation and maintenance of the noradrenergic neurotransmitter phenotype. The encoded protein has also been shown to regulate transcription of the alpha3 nicotinic acetylcholine receptor gene. Mutations in this gene have been associated with autosomal recessive congenital fibrosis of the extraocular muscles.

Research Areas: Epigenetics and nuclear signaling; Neuroscience

Target Protein: PHOX2A

Applications: WB, ELISA

Reactivity: Human, Rat, Mouse

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: Paired mesoderm homeobox protein 2A

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

UniProt Accession: Human: O14813; Mouse: Q62066; Rat: Q62782

Synonyms: Paired mesoderm homeobox protein 2A;ARIX1 homeodomain protein;Aristaless homeobox protein homolog;Paired-like homeobox 2A

GeneID: Human: 401

Research Use Only