Product Description

PI3K p85 beta Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS67364-50, BS67364-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: Regμlatory subunit of phosphoinositide-3-kinase (PI3K), a kinase that phosphorylates PtdIns(4, 5)P2 (Phosphatidylinositol 4, 5-bisphosphate) to generate phosphatidylinositol 3, 4, 5-trisphosphate (PIP3). PIP3 plays a key role by recruiting PH domain-containing proteins to the membrane, including AKT1 and PDPK1, activating signaling cascades involved in cell growth, survival, proliferation, motility and morphology. Binds to activated (phosphorylated) protein-tyrosine kinases, through its SH2 domain, and acts as an adapter, mediating the association of the p110 catalytic unit to the plasma membrane. Indirectly regμlates autophagy.

Category: Primary Antibody

Reactivity: Human, Mouse, Rat, Bovine

Host: Rabbit

Applications: WB

Alternate Names: Phosphatidylinositol 3-kinase regμlatory subunit beta, PI3-kinase regμlatory subunit beta, PI3K regμlatory subunit beta, PtdIns-3-kinase regμlatory subunit beta, Phosphatidylinositol 3-kinase 85 kDa regμlatory subunit beta, PI3-kinase subunit p85-beta, PtdIns-3-kinase regμlatory subunit p85-beta

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human PI3K p85 beta. The exact sequence is proprietary.

Dilution: WB (1/500 - 1/1000)

Purification: The antibody was purified by immunogen affinity chromatography.

Specificity: Recognizes endogenous levels of PI3K p85 beta protein.

Molecular Weight: ~ 95 kDa

Pathway: PI3K AKT signaling.

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: O00459

Product: Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.

Research Use Only