PI3R6 Polyclonal Antibody - BT-AP13028

PI3R6 Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP13028-20, BT-AP13028-50, BT-AP13028-100

Citations, Manuals and MSDS Available upon request.

Background: Phosphoinositide 3-kinase gamma is a lipid kinase that produces the lipid second messenger phosphatidylinositol 3,4,5-trisphosphate. The kinase is composed of a catalytic subunit and one of several regulatory subunits, and is chiefly activated by G protein-coupled receptors. This gene encodes a regulatory subunit, and is distantly related to the phosphoinositide-3-kinase, regulatory subunit 5 gene which is located adjacent to this gene on chromosome 7. The orthologous protein in the mouse binds to both the catalytic subunit and to G(beta/gamma), and mediates activation of the kinase subunit downstream of G protein-coupled receptors. Alternative splicing results in multiple transcript variants.

Research Areas: Signal transduction

Target Protein: PIK3R6

Applications: WB, ELISA

Reactivity: Human, Rat, Mouse

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: Phosphoinositide 3-kinase regulatory subunit 6

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

UniProt Accession: Human: Q5UE93; Mouse: Q3U6Q4

Synonyms: Phosphoinositide 3-kinase regulatory subunit 6;Phosphoinositide 3-kinase gamma adapter protein of 87 kDa;p84 PI3K adapter protein;p84 PIKAP;p87 PI3K adapter protein;p87PIKAP

GeneID: Human: 146850

Research Use Only