PIGA Polyclonal Antibody - BT-AP13044

PIGA Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP13044-20, BT-AP13044-50, BT-AP13044-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes a protein required for synthesis of N-acetylglucosaminyl phosphatidylinositol (GlcNAc-PI), the first intermediate in the biosynthetic pathway of GPI anchor. The GPI anchor is a glycolipid found on many blood cells and which serves to anchor proteins to the cell surface. Paroxysmal nocturnal hemoglobinuria, an acquired hematologic disorder, has been shown to result from mutations in this gene. Alternate splice variants have been characterized. A related pseudogene is located on chromosome 12.

Research Areas: Cardiovascular

Target Protein: PIGA

Applications: WB, ELISA

Reactivity: Human, Mouse

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: Phosphatidylinositol N-acetylglucosaminyltransferase subunit A

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

UniProt Accession: Human: P37287; Mouse: Q64323

Synonyms: Phosphatidylinositol N-acetylglucosaminyltransferase subunit A;EC 2.4.1.198;GlcNAc-PI synthesis protein;Phosphatidylinositol-glycan biosynthesis class A protein;PIG-A

GeneID: Human: 5277

Research Use Only