Product Description

PIM1 Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS65634-50, BS65634-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: The protein encoded by this gene belongs to the Ser/Thr protein kinase family, and PIM subfamily. This gene is expressed primarily in B-lymphoid and myeloid cell lines, and is overexpressed in hematopoietic malignancies and in prostate cancer. It plays a role in signal transduction in blood cells, contributing to both cell proliferation and survival, and thus provides a selective advantage in tumorigenesis. Both the human and orthologous mouse genes have been reported to encode two isoforms (with preferential cellμlar localization) resμlting from the use of alternative in-frame translation initiation codons, the upstream non-AUG (CUG) and downstream AUG codons (PMIDs:16186805, 1825810).[provided by RefSeq, Aug 2011]

Category: Primary Antibody

Reactivity: Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Rabbit, Sheep, Guinea Pig

Host: Rabbit

Applications: FCM

Alternate Names: Oncogene PIM 1, Oncogene PIM1, PIM 1, pim 1 kinase 44 kDa isoform, Pim 1 kinase, pim 1 oncogene (proviral integration site 1), Pim 1 oncogene, PIM, PIM1, pim1 kinase 44 kDa isoform, PIM1_HUMAN, Pim2, PIM3, Proto oncogene serine/threonine protein kinase Pim 1, Proto-oncogene serine/threonine-protein kinase Pim-1, Proviral integration site 1, Proviral integration site 2.

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: KLH conjugated synthetic peptide derived from human PIM1

Dilution: Flow-Cyt=1ug/Test

Purification: affinity purified by Protein A

Specificity: PIM1 Polyclonal Antibody detects endogenous levels of PIM1 protein.

Molecular Weight: 45kD

Pathway: Examples of Crosstalk Between Post-translational Modifications,

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: P11309

Product: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Research Use Only