Product Description

PINCH (3C12) Monoclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: MB3154-50, MB3154-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: The protein encoded by this gene is an adaptor protein which contains five LIM domains, or double zinc fingers. The protein is likely involved in integrin signaling through its LIM domain-mediated interaction with integrin-linked kinase, found in focal adhesion plaques. It is also thought to act as a bridge linking integrin-linked kinase to NCK adaptor protein 2, which is involved in growth factor receptor kinase signaling pathways. Its localization to the periphery of spreading cells also suggests that this protein may play a role in integrin-mediated cell adhesion or spreading. Several transcript variants encoding different isoforms have been found for this gene.

Category: Primary Antibody

Reactivity: Human

Host: Mouse

Applications: WB, ICC/IF, FC, IP

Alternate Names: LIMS1, PINCH, PINCH1, LIM and senescent cell antigen-like-containing domain protein 1, Particμlarly interesting new Cys-His protein 1, PINCH-1, Renal carcinoma antigen NY-REN-48

Clonality: Monoclonal

Conjugate: Unconjugated

Modification: Unmodified

Immunogen: Purified recombinant fragment of human PINCH expressed in E. Coli.

Dilution: WB: 1/500-1/1000 IF: 1/50-1/200 IP: 1/20 FC: 1/50-1/100

Purification: Affinity Purified

Specificity: IgG1

Molecular Weight: Calcμlated MW: 37 kDa, Observed MW: 37 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: P48059

Product: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

Research Use Only