Product Description

PKM2 Monoclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: MB0189-50, MB0189-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: The PKM2 (pyruvate kinase, muscle) gene encodes the M1- and M2-type isoenzymes through alternative splicing events. Both M1- and M2-type isoforms exists as tetramers and are stimμlated by fructose 1, 6-bisphosphate. In addition, both isoforms exhibit thyroid hormone binding activity and may be referred to as CTHBP (cytosolic thyroid hormone-binding protein) or THBP1.

Category: Primary Antibody

Reactivity: Human, Mouse, Rat, Monkey

Host: Mouse

Applications: WB, ICC/IF

Alternate Names: PK 1, PK 2, PK 3, PK Muscle type, PK1, PK2, Pk3, PKL, PKLR, PKM 2, PKM, PYKM, Pyruvate kinase 1, Pyruvate kinase 2/3, Pyruvate kinase 3, Pyruvate kinase isozyme R/L, Pyruvate kinase isozymes M1/M2, Pyruvate kinase liver and blood cell, Pyruvate kinase liver and RBC, Pyruvate kinase liver and RBC type, Pyruvate kinase M2, Pyruvate kinase muscle, Pyruvate kinase muscle isozyme, Pyruvate kinase type L, R type/L type pyruvate kinase, Red cell/liver pyruvate kinase, RPK, TCB, THBP 1, THBP1, Thyroid hormone binding protein cytosolic, CTHBP, Cytosolic thyroid hormone binding protein, MGC3932, OIP 3, Oip3, Tumor M2-PK, p58, OIP-3, KPYM_HUMAN

Clonality: Monoclonal

Conjugate: Unconjugated

Modification: Unmodified

Immunogen: Purified recombinant human PKM2 protein fragments expressed in E.coli.

Dilution: WB: 1:500~1:1000
IF: 1:50~1:200

Purification: The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: PKM2 monoclonal antibody detects endogenous levels of PKM2 protein.

Molecular Weight: ~ 56 kDa

Pathway: Warburg Effect, Insμlin &Glucose Signaling, Glutamine Metabolism,

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: P14618

Product: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Research Use Only