Product Description

PKN3 Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP13131-20, BT-AP13131-50, BT-AP13131-100

Citations, Manuals and MSDS Available upon request.

Background: Catalytic activity:ATP + a protein = ADP + a phosphoprotein.,The C1 domain does not bind the diacylglycerol (DAG).,enzyme regulation:Two specific sites, Thr-718 (activation loop of the kinase domain) and Thr-860 (turn motif), need to be phosphorylated for its full activation.,Contributes to invasiveness in malignant prostate cancer.,PTM:Autophosphorylated.,Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.,Contains 1 AGC-kinase C-terminal domain.,Contains 1 protein kinase domain.,Contains 3 REM (Hr1) repeats.,subcellular location:Nuclear and perinuclear Golgi region.,tissue specificity:Expressed in prostate tumors and various cancer cell lines. Not expressed in adult tissues.,

Research Areas: Signal transduction

Target Protein: PKN3

Applications: WB, ELISA

Reactivity: Human, Mouse

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: Serine/threonine-protein kinase N3

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

UniProt Accession: Human: Q6P5Z2; Mouse: Q8K045

Synonyms: Serine/threonine-protein kinase N3;EC 2.7.11.13;Protein kinase PKN-beta;Protein-kinase C-related kinase 3

GeneID: Human: 29941

Research Use Only