PLAGL1 Monoclonal Antibody - BT-MCA2371

PLAGL1 Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Number: BT-MCA2371-50, BT-MCA2371-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes a C2H2 zinc finger protein with transactivation and DNA-binding activities. It has been shown to have anti-proliferative properties, and thus thought to function as a tumor suppressor. In addition, overexpression of this gene during fetal development is believed to underlie the rare disorder, transient neonatal diabetes mellitus (TNDM). This gene is imprinted, with preferential expression of the paternal allele in many tissues, however, biallelic expression has been noted in peripheral blood leucocytes. A recent study reports that tissue-specific imprinting results from variable utilization of monoallelic and biallelic promoters. Many transcript variants differing in the 5' UTR and encoding two different isoforms, have been found for this gene.

Research Areas: Neuroscience

Target Protein: PLAGL1

Applications: IHC

Reactivity: Human

Clonality: Monoclonal

Clone ID: 8D8C5

Host: Mouse

Isotype: Mouse IgG1

Full Product Name: PLAGL1

Immunogen: Purified recombinant fragment of human PLAGL1 (AA: 118-222) expressed in E. Coli.

Storage: 4°C|-20°C for long term storage

Formulation: Purified antibody in PBS with 0.05% sodium azide

Molecular Weight (Da): 50.8kDa

UniProt Accession: Q9UM63

Synonyms: ZAC, LOT1, ZAC1

GeneID: 5325

Research Use Only