PLAU Monoclonal Antibody - BT-MCA3959

PLAU Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Number: BT-MCA3959-50, BT-MCA3959-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes a secreted serine protease that converts plasminogen to plasmin. The encoded preproprotein is proteolytically processed to generate A and B polypeptide chains. These chains associate via a single disulfide bond to form the catalytically inactive high molecular weight urokinase-type plasminogen activator (HMW-uPA). HMW-uPA can be further processed into the catalytically active low molecular weight urokinase-type plasminogen activator (LMW-uPA). This low molecular weight form does not bind to the urokinase-type plasminogen activator receptor. Mutations in this gene may be associated with Quebec platelet disorder and late-onset Alzheimer's disease. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed.

Research Areas: Neuroscience

Target Protein: PLAU

Applications: WB, ICC, FCM

Reactivity: Human

Clonality: Monoclonal

Clone ID: 6B6A3

Host: Mouse

Isotype: Mouse IgG1

Full Product Name: PLAU

Immunogen: Purified recombinant fragment of human PLAU (AA: 107-379) expressed in E. Coli.

Storage: 4°C|-20°C for long term storage

Formulation: Purified antibody in PBS with 0.05% sodium azide

Molecular Weight (Da): 48.5KDa

UniProt Accession: P00749

Synonyms: ATF, QPD, UPA, URK, u-PA, BDPLT5

GeneID: 5328

Research Use Only