PLCG2 Monoclonal Antibody - BT-MCA2036

PLCG2 Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Number: BT-MCA2036-50, BT-MCA2036-100

Citations, Manuals and MSDS Available upon request.

Background: The protein encoded by this gene is a transmembrane signaling enzyme that catalyzes the conversion of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate to 1D-myo-inositol 1,4,5-trisphosphate (IP3) and diacylglycerol (DAG) using calcium as a cofactor. IP3 and DAG are second messenger molecules important for transmitting signals from growth factor receptors and immune system receptors across the cell membrane. Mutations in this gene have been found in autoinflammation, antibody deficiency, and immune dysregulation syndrome and familial cold autoinflammatory syndrome 3.

Research Areas: Cardiovascular

Target Protein: PLCG2

Applications: WB, ICC, FCM

Reactivity: Human

Clonality: Monoclonal

Clone ID: 3A8B6

Host: Mouse

Isotype: Mouse IgG2b

Full Product Name: PLCG2

Immunogen: Synthesized peptide of human PLCG2 (AA: phospho-Tyrosine 753 of human Phospholipase Cg2(cERDINSLpYDVSRMYV)).

Storage: 4°C|-20°C for long term storage

Formulation: Purified antibody in PBS with 0.05% sodium azide.

Molecular Weight (Da): 148kDa

UniProt Accession: P16885

Synonyms: FCAS3, APLAID, PLC-IV, PLC-gamma-2

GeneID: 5336

Research Use Only