Product Description

PLOD2 Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA34143-50, RA34143-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 (PLOD2) Homo sapiens The protein encoded by this gene is a membrane-bound homodimeric enzyme that is localized to the cisternae of the rough endoplasmic reticulum. The enzyme (cofactors iron and ascorbate) catalyzes the hydroxylation of lysyl residues in collagen-like peptides. The resultant hydroxylysyl groups are attachment sites for carbohydrates in collagen and thus are critical for the stability of intermolecular crosslinks. Some patients with Ehlers-Danlos syndrome type VIB have deficiencies in lysyl hydroxylase activity. Mutations in the coding region of this gene are associated with Bruck syndrome. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008],

Reactivity: Human, Rat, Mouse

Host: Rabbit

Applications: WB, ELISA

Clonality: Polyclonal

Dilution: WB 1:500-2000 ELISA 1:5000-20000

Molecular Weight: 81

Protein Molecular Weight (kDa): 81

Storage: -20°C/1 year

Human Gene ID: 5352

Human SwissProt Number: O00469

Condition: Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Research Use Only