POLR2A Monoclonal Antibody - BT-MCA2127

POLR2A Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Number: BT-MCA2127-50, BT-MCA2127-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes the largest subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. The product of this gene contains a carboxy terminal domain composed of heptapeptide repeats that are essential for polymerase activity. These repeats contain serine and threonine residues that are phosphorylated in actively transcribing RNA polymerase. In addition, this subunit, in combination with several other polymerase subunits, forms the DNA binding domain of the polymerase, a groove in which the DNA template is transcribed into RNA.

Research Areas: Epigenetics and Nuclear Signaling

Target Protein: POLR2A

Clonality: Monoclonal

Clone ID: 1A6B1

Host: Mouse

Isotype: Mouse IgG2b

Full Product Name: POLR2A

Immunogen: Purified recombinant fragment of human POLR2A (AA: 128-258) expressed in E. Coli.

Storage: 4°C|-20°C for long term storage

Formulation: Purified antibody in PBS with 0.05% sodium azide

Molecular Weight (Da): 217kDa

UniProt Accession: P24928

Synonyms: RPB1, RPO2, POLR2, POLRA, RPBh1, RPOL2, RpIILS, hsRPB1, hRPB220

GeneID: 5430

Research Use Only