PON2 Polyclonal Antibody - BT-AP13227

PON2 Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP13227-20, BT-AP13227-50, BT-AP13227-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes a member of the paraoxonase gene family, which includes three known members located adjacent to each other on the long arm of chromosome 7. The encoded protein is ubiquitously expressed in human tissues, membrane-bound, and may act as a cellular antioxidant, protecting cells from oxidative stress. Hydrolytic activity against acylhomoserine lactones, important bacterial quorum-sensing mediators, suggests the encoded protein may also play a role in defense responses to pathogenic bacteria. Mutations in this gene may be associated with vascular disease and a number of quantitative phenotypes related to diabetes. Alternatively spliced transcript variants encoding different isoforms have been described.

Research Areas: Cardiovascular; Metabolism; Neuroscience; Signal transduction

Target Protein: PON2

Applications: WB, ELISA

Reactivity: Human, Rat, Mouse

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: Serum paraoxonase/arylesterase 2

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

UniProt Accession: Human: Q15165; Mouse: Q62086; Rat: Q6AXM8

Synonyms: Serum paraoxonase/arylesterase 2;PON 2;EC 3.1.1.2;EC 3.1.1.81;Aromatic esterase 2;A-esterase 2;Serum aryldialkylphosphatase 2

GeneID: Human: 5445

Research Use Only