Product Description

PP1 alpha Monoclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: MB66487-50, MB66487-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: Type 1 protein phosphatase (PP1), a serine/threonine phosphatase, is highly conserved in eukaryotic cells. Four isoforms of PP1 have been characterized: PP1α, PP1δ, PP1γ1 and PP1γ2 . Involvement in cell cycle regμlation is one of the biological functions of PP1 . It has been illustrated that PP1 dephosphorylates Rb and cdc25 during mitosis . A cell cycle-dependent phosphorylation at Thr320 of PP1α by cdc2 kinase inhibits PP1α activity .

Category: Primary Antibody

Reactivity: Human

Host: Mouse

Applications: WB, IHC, IF/ICC

Alternate Names: PPP1A, Serine/threonine-protein phosphatase PP1-alpha catalytic subunit, PP-1A

Clonality: Monoclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: Purified recombinant human PPP1A protein fragments expressed in E.coli.

Dilution: WB (1/500 - 1/1000), IHC (1/50 - 1/100), IF/ICC (1/50 - 1/100)

Purification: The antibody was purified by immunogen affinity chromatography.

Specificity: Recognizes endogenous levels of PP1 alpha protein.

Molecular Weight: ~ 38 kDa

Pathway: MAPK Erk in Growth and Differentiation Pathway, Dopamine Signaling in Parkinson's Disease Plathway, Translational Contral Regμlation of elF2

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: P62136

Product: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

Research Use Only