Product Description

PP2A-Aβ Polyclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: BS65382-50, BS65382-100

Product: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Swiss-Prot: P30154

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB, IHC-P, IF (paraffin section), ELISA

All Applications: Western Blot: 1/500 - 1/2000.IHC-p:1:50-300 ELISA: 1/20000. Not yet tested in other applications.

Background: protein phosphatase 2 scaffold subunit Abeta(PPP2R1B) Homo sapiens This gene encodes a constant regulatory subunit of protein phosphatase 2. Protein phosphatase 2 is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The constant regulatory subunit A serves as a scaffolding molecule to coordinate the assembly of the catalytic subunit and a variable regulatory B subunit. This gene encodes a beta isoform of the constant regulatory subunit A. Mutations in this gene have been associated with some lung and colon cancers. Alternatively spliced transcript variants have been described. [provided by RefSeq, Apr 2010],

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: PP2A-Aβ Polyclonal Antibody detects endogenous levels of PP2A-Aβ protein.

Bioworld Molecular Weight: ~66 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western Blot analysis of various cells using PP2A-Aβ Polyclonal Antibody, Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using PPP2R1B Antibody. The picture on the right is blocked with the synthesized peptide., Western blot analysis of lysates from HeLa and Jurkat cells, using PPP2R1B Antibody. The Lane on the right is blocked with the synthesized peptide.

Alternative Name: PPP2R1B; Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform; PP2A subunit A isoform PR65-beta; PP2A subunit A isoform R1-beta

Immunogen: The antiserum was produced against synthesized peptide derived from human PPP2R1B. AA range:552-601

Conjugate: Unconjugated

Modification: Unmodified