PPIG Polyclonal Antibody - BT-AP13258

PPIG Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP13258-20, BT-AP13258-50, BT-AP13258-100

Citations, Manuals and MSDS Available upon request.

Background: Catalytic activity:Peptidylproline (omega=180) = peptidylproline (omega=0).,The RS domain is required for the interaction with the phosphorylated C-terminal domain of RNA polymerase II.,enzyme regulation:Cyclosporin A (CsA)-sensitive.,PPIases accelerate the folding of proteins.,PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.,PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. May be implicated in the folding, transport, and assembly of proteins. May play an important role in the regulation of pre-mRNA splicing.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,Belongs to the cyclophilin-type PPIase family.,Contains 1 PPIase cyclophilin-type domain.,subcellular location:Colocalizes with RNA splicing factors at nuclear speckles.,subunit:Interacts with CLK1, PNN and with the phosphorylated C-terminal domain of RNA polymerase II.,tissue specificity:Ubiquitous.,

Research Areas: Epigenetics and nuclear signaling; Signal transduction

Target Protein: PPIG

Applications: WB, ELISA

Reactivity: Human, Rat, Mouse

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: Peptidyl-prolyl cis-trans isomerase G

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

UniProt Accession: Human: Q13427; Mouse: A2AR02; Rat: O55035

Synonyms: Peptidyl-prolyl cis-trans isomerase G;PPIase G;Peptidyl-prolyl isomerase G;EC 5.2.1.8;CASP10;Clk-associating RS-cyclophilin;CARS-Cyp;CARS-cyclophilin;SR-cyclophilin;SR-cyp;SRcyp;C

GeneID: Human: 9360

Research Use Only