PPP2R4 Monoclonal Antibody - BT-MCA3750

PPP2R4 Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Number: BT-MCA3750-50, BT-MCA3750-100

Citations, Manuals and MSDS Available upon request.

Background: Protein phosphatase 2A is one of the four major Ser/Thr phosphatases and is implicated in the negative control of cell growth and division. Protein phosphatase 2A holoenzymes are heterotrimeric proteins composed of a structural subunit A, a catalytic subunit C, and a regulatory subunit B. The regulatory subunit is encoded by a diverse set of genes that have been grouped into the B/PR55, B'/PR61, and B''/PR72 families. These different regulatory subunits confer distinct enzymatic specificities and intracellular localizations to the holozenzyme. The product of this gene belongs to the B' family. This gene encodes a specific phosphotyrosyl phosphatase activator of the dimeric form of protein phosphatase 2A. Alternative splicing results in multiple transcript variants encoding different isoforms.

Research Areas: Signal transduction

Target Protein: PPP2R4

Applications: IHC, ICC, FCM

Reactivity: Human

Clonality: Monoclonal

Clone ID: 4D9

Host: Mouse

Isotype: Mouse IgG1

Full Product Name: PPP2R4

Immunogen: Purified recombinant fragment of human PPP2R4 expressed in E. Coli.

Storage: 4°C|-20°C for long term storage

Formulation: Purified antibody in PBS with 0.05% sodium azide

Molecular Weight (Da): 41kDa

UniProt Accession: Q15257

Synonyms: PP2A, PR53, PTPA

GeneID: 5524

Research Use Only