PPR1A Polyclonal Antibody - BT-AP13271

PPR1A Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP13271-20, BT-AP13271-50, BT-AP13271-100

Citations, Manuals and MSDS Available upon request.

Background: Inhibitor of protein-phosphatase 1. This protein may be important in hormonal control of glycogen metabolism. Hormones that elevate intracellular cAMP increase I-1 activity in many tissues. I-1 activation may impose cAMP control over proteins that are not directly phosphorylated by PKA. Following a rise in intracellular calcium, I-1 is inactivated by calcineurin (or PP2B). Does not inhibit type-2 phosphatases.,PTM:Phosphorylation of Thr-35 is required for activity.,Belongs to the protein phosphatase inhibitor 1 family.,subunit:Interacts with PPP1R15A.,

Research Areas: Metabolism; Signal transduction

Target Protein: PPP1R1A

Applications: WB, ELISA

Reactivity: Human, Mouse, Rat

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: Protein phosphatase 1 regulatory subunit 1A

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

UniProt Accession: Human: Q13522; Mouse: Q9ERT9; Rat: P19103

Synonyms: Protein phosphatase 1 regulatory subunit 1A;Protein phosphatase inhibitor 1;I-1;IPP-1

GeneID: Human: 5502

Research Use Only