PR Monoclonal Antibody - BT-MCA1058

PR Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Number: BT-MCA1058-50, BT-MCA1058-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes a member of the steroid receptor superfamily. The encoded protein mediates the physiological effects of progesterone, which plays a central role in reproductive events associated with the establishment and maintenance of pregnancy. This gene uses two distinct promotors and translation start sites in the first exon to produce several transcript variants, both protein coding and non-protein coding. Two of the isoforms (A and B) are identical except for an additional 165 amino acids found in the N-terminus of isoform B and mediate their own response genes and physiologic effects with little overlap.

Research Areas: Epigenetics and Nuclear Signaling; Signal Transduction; Neuroscience; Cancer

Target Protein: PGR

Applications: WB, IHC-p, IF, ELISA

Reactivity: Human

Clonality: Monoclonal

Host: Mouse

Isotype: IgG

Full Product Name: Progesterone receptor

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

UniProt Accession: Human: P06401; Mouse: Q00175

Synonyms: PGR; NR3C3; Progesterone receptor; PR; Nuclear receptor subfamily 3 group C member 3

GeneID: Human: 5241

Research Use Only