PR3 Monoclonal Antibody - BT-MCA1060

PR3 Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Number: BT-MCA1060-50, BT-MCA1060-100

Citations, Manuals and MSDS Available upon request.

Background: Catalytic activity:Hydrolysis of proteins, including elastin, by preferential cleavage: -Ala-|-Xaa- andgt; -Val-|-Xaa-.,function:Polymorphonuclear leukocyte serine protease that degrades elastin, fibronectin, laminin, vitronectin, and collagen types I, III, and IV (in vitro) and causes emphysema when administered by tracheal insufflation to hamsters.,online information:Proteinase 3 entry,similarity:Belongs to the peptidase S1 family. Elastase subfamily.,similarity:Contains 1 peptidase S1 domain.,

Research Areas: Signal transduction

Target Protein: PRTN3

Applications: WB, ELISA

Reactivity: Human

Clonality: Monoclonal

Host: Mouse

Isotype: IgG

Full Product Name: Myeloblastin

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

UniProt Accession: Human: P24158; Mouse: Q61096

Synonyms: PRTN3; MBN; Myeloblastin; AGP7; C-ANCA antigen; Leukocyte proteinase 3; PR-3; PR3; Neutrophil proteinase 4; NP-4; P29; Wegener autoantigen

GeneID: Human: 5657

Research Use Only