PRAME Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: A14507-20, A14507-100
Citations, Manuals and MSDS Available upon request.
Background: This gene encodes an antigen that is preferentially expressed in human melanomas and that is recognized by cytolytic T lymphocytes. It is not expressed in normal tissues, except testis. The encoded protein acts as a repressor of retinoic acid receptor, and likely confers a growth advantage to cancer cells via this function. Alternative splicing results in multiple transcript variants.
Category: Polyclonal Antibodies
Applications: WB, ELISA
Cross-reactivity: Human, Mouse, Rat
Protein Weight: 58kDa
Observed Molecular Weight: 58kDa
Immunogen: Recombinant protein (or fragment)
Species: Human
GeneID: 23532
SWISS: P78395
Alternate Names: MAPE; OIP4; CT130; OIP-4; PRAME
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.01% thimerosal, 50% glycerol, pH 7.3.
Recommended Dilutions: WB, 1:500 - 1:2000 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Research Areas: Epigenetics Nuclear Signaling, Nuclear Receptor Signaling, Cancer, Tumor biomarkers.
NCBI Alias: PRAME
Research Use Only